Best Western - accommodation in Otay Mesa
More than just hotels
Apartments, cabins, holiday rentals and more, plus millions of reviews from Aussie & Kiwi travellers
Flexibility matters
24/7 support, so you can book with confidence
Unlock member prices with Mates Rates
You could save 10% or more on over 100,000 hotels right now.
Check hotel availability in Otay Mesa
Featured Otay Mesa Best Western accommodation
Best Western Seven Seas
411 Hotel Circle South, San Diego, CA
The price is AU$162 per night
AU$162
includes taxes & fees
26 Nov - 27 Nov
Best Western Seven Seas: Business-friendly hotel with free WiFi and free parking. Located in a shopping district.
Free cancellation
Reserve now, pay when you stay
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place, San Diego, CA
The price is AU$186 per night
AU$186
includes taxes & fees
1 Dec - 2 Dec
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area : Business-friendly hotel with free breakfast and free WiFi. Located in a shopping district.
Free cancellation
Reserve now, pay when you stay
Best Western Chula Vista/Otay Valley Hotel
4450 Main Street, Chula Vista, CA
The price is AU$178 per night
AU$178
includes taxes & fees
15 Dec - 16 Dec
Best Western Chula Vista/Otay Valley Hotel: Business-friendly hotel with free breakfast and free WiFi. Located near the airport.
Free cancellation
Reserve now, pay when you stay
Best Western Yacht Harbor Hotel
5005 N Harbor Dr, San Diego, CA
The price is AU$229 per night
AU$229
includes taxes & fees
26 Nov - 27 Nov
Best Western Yacht Harbor Hotel: Business-friendly hotel with free breakfast and free WiFi. Located near the boardwalk.
Free cancellation
Reserve now, pay when you stay
Best Western Americana Inn
815 W San Ysidro Boulevard, San Ysidro, CA
The price is AU$181 per night
AU$181
includes taxes & fees
2 Dec - 3 Dec
Best Western Americana Inn: Hotel with free breakfast and free WiFi. Located in the entertainment district.
Free cancellation
Reserve now, pay when you stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Western Accommodation in Otay Mesa
Search for hotels in Otay Mesa on Wotif. You can easily find your hotels in Otay Mesa using one of the methods below:
- View our selection of featured hotels in Otay Mesa
- Use the map to find hotels in the Otay Mesa neighbourhood you prefer
- Use the filters to see hotels in a specific area of Otay Mesa, select a specific theme, brand, or hotel class from basic to luxury hotels in Otay Mesa
- Enter your travel dates to view the best deals on hotels in Otay Mesa - while they last
New reviews! Best hotels in Otay Mesa
Wotif Verified Review
5 / 5
Amazing view!
A verified traveller stayed at Wyndham San Diego Bayside
Posted 22 hours ago
Neighbourhoods
Nearby cities
Near an airport
Near an Attraction
Hotel themes
Hotel brands
^Eligibility requirements and conditions apply.