Holiday Rentals in Santee
More than just hotels
Apartments, cabins, holiday rentals and more, plus millions of reviews from Aussie & Kiwi travellers
Flexibility matters
24/7 support, so you can book with confidence
Unlock member prices with Mates Rates
You could save 10% or more on over 100,000 hotels right now.
Check rental availability in Santee
Holiday Rentals in Santee

Sunsets on Lake Marion

Executive 2 BR/2 BA Lakefront Corner Suite Condo

Lake Marion - Majestic Big Water View!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Lakeview Condo close to Fishing, golfing, and hiking.

Bells Marina & Resort

Pet friendly country cottage with large fenced-in yard & horses on property

Lake Marion Lakehouse with 180° lake view

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

Country Resting Spot

Sweet Marion - Dock + Boat Ramp + Spa + Lakefront!

Beautiful lake home to make your family vacation extra special!
Other types of properties in Santee you may be interested in

Baymont by Wyndham Santee
Holiday Accommodation Santee
You’re the type of person who wants to be right in the middle of it all, but still have your own space. You want to be able to take care of everything yourself, but also get plenty of R&R. Well, holiday rentals in Santee are ready to roll out the welcome mat. We mean that literally—they probably do have a welcome mat. It’s all those little things that will make you fall in love with this type of accommodation, and with Santee itself. Once you’ve stayed in a holiday rental, you’ll wonder why you ever stayed anywhere else.
Santee holiday houses have everything you could need in a place to stay, along with several things you probably never even thought you needed. Towels and linens? Check. Cooking utensils? Check. Dog treats for the pupper? Well, you might want to bring your own to your pet-friendly holiday house, just in case. (He’s a picky little prince anyway, right?) But otherwise you’re good to go. You might even find some games for the little ones, if you’re bringing the family along.
If you are bringing the kids, don’t let that dissuade you from looking for the finer things. Luxury is the name of the game in Santee, and house accommodation is no different. Sure, it should feel like a home away from home—but more like a really fancy home, where you don’t have to worry about cleaning or mowing the lawn. Yes, it’s as great as it sounds.
Make your next getaway truly your own. We’ve got plenty of holiday accommodation in Santee with your name on it, so pack up your favourite books, wine and that playlist of summer hits from 2003. It’s your time to shine.