Accommodation in Otay Mesa West from AU$140

More than just hotels
Apartments, cabins, holiday rentals and more, plus millions of reviews from Aussie & Kiwi travellers

Flexibility matters
24/7 support, so you can book with confidence

Unlock member prices with Mates Rates
You could save 10% or more on over 100,000 hotels right now.

Check hotel availability in Otay Mesa West

Tonight
Check prices in Otay Mesa West for tonight, 5 Nov - 6 Nov
Tomorrow night
Check prices in Otay Mesa West for tomorrow night, 6 Nov - 7 Nov
This weekend
Check prices in Otay Mesa West for this weekend, 8 Nov - 10 Nov
Next weekend
Check prices in Otay Mesa West for next weekend, 15 Nov - 17 Nov

Otay Mesa West stays as unique as you are

Best Hotels in Otay Mesa West

Don't see what you're looking for?
See all available properties in Otay Mesa West
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Otay Mesa West

Are you heading to San Diego? You should stop by and reach the Otay Mesa West neighbourhood, located 18 kilometres southeast of the town centre.

San Diego is where you'll find an impressive number of iconic things to see, such as the San Diego Zoo, Seaworld and the San Diego State University.

Stopping in at Fruit Barr Caffe is a great way to kick off your day in Otay Mesa West. Just follow the scent of roasted coffee beans! Unfortunately, our bodies can't run on caffeine alone. Check out the menu at Little Caesars Pizza when your stomach starts to growl. Before strolling back to the hotel, why not pull up a stool at Over the Border for a nightcap? Whether you're a beer or wine drinker, you'll be well looked after here.

Accommodation options near Otay Mesa West

Booking a place to stay in Otay Mesa West's centre could be difficult if you're after a last-minute option, but you'll surely be safe knowing alternatives are available in the San Ysidro hotels guide and in the Wotif Chula Vista hotels guide. San Ysidro is home to the Rodeway Inn and Quality Inn & Suites Near The Border, while in Chula Vista you can check out the Holiday Inn Express San Diego South - Chula Vista and La Quinta Inn San Diego Chula Vista.

Otay Mesa West features some fabulous places to stay. So, when you're ready to explore the delights of San Diego, let Wotif take you there!

Otay Mesa West hotels essential information

Accommodation
6,290 hotels
Lowest Price
AU$140
Highest Price
AU$395
Popular hotels
Wyndham Garden San Diego Near SeaWorld, Best Western Seven Seas, Wyndham San Diego Bayside, Manchester Grand Hyatt San Diego, The Dana on Mission Bay, Paradise Point Resort & Spa, Comfort Inn Sea World Area, Bay Club Hotel & Marina, California Suites Hotel, Handlery Hotel, Kings Inn San Diego, Hyatt Regency Mission Bay Spa and Marina

New reviews! Best hotels in Otay Mesa West

^Eligibility requirements and conditions apply.